Dianthus Therapeutics

Clinical-stage biotechnology company developing precision antibody therapeutics targeting the complement system for severe autoimmune and inflammatory diseases.

Location
New York, New York, USA
Founded
2021
Categories
biotech, autoimmune, antibody-therapeutics, complement-pathway

Notes

Dianthus Therapeutics is a clinical-stage biotechnology company focused on developing precision antibody therapeutics targeting the complement system. The complement system is part of the innate immune system and plays a role in various autoimmune and inflammatory diseases.

The company was created through a merger between Dianthus and Magenta Therapeutics' autoimmune disease program. Dianthus is developing DNTH103, a monoclonal antibody targeting C5aR1 (complement component 5a receptor 1), for the treatment of severe autoimmune diseases.

Dianthus is publicly traded on NASDAQ under the ticker symbol DNTH.

Team

  • Matthew Gline - CEO
  • Leadership team available on company website

Additional Research Findings

  • Portfolio company of Bain Capital Life Sciences
  • Founded in 2021
  • Publicly traded: NASDAQ (DNTH)
  • Merged with Magenta Therapeutics autoimmune program in 2023
  • Lead candidate: DNTH103 targeting C5aR1
  • Focus on complement-mediated autoimmune diseases
  • Target indications include myasthenia gravis and other complement-mediated conditions
  • Headquarters in New York City

Sources