Flexion Therapeutics

Biopharmaceutical company focused on developing treatments for musculoskeletal conditions. Best known for ZILRETTA, an extended-release corticosteroid for osteoarthritis knee pain. Acquired by Pacira BioSciences in 2021.

Location
Burlington, Massachusetts, USA
Founded
2007
Investors
1
Categories
therapeutics, biotech, musculoskeletal, pain-management, acquired

Notes

Flexion Therapeutics was a biopharmaceutical company that developed ZILRETTA (triamcinolone acetonide extended-release injectable suspension), the first and only extended-release intra-articular therapy approved by the FDA for osteoarthritis knee pain. ZILRETTA was approved by the FDA in October 2017.

Acquired by Pacira BioSciences in November 2021 for approximately $630 million ($8.50 per share in cash). The acquisition brought together Pacira's expertise in non-opioid pain management with Flexion's ZILRETTA product for osteoarthritis.

The company was founded in 2007 and went public in 2014. Before the acquisition, Flexion had raised over $500 million in equity financings and had built a commercial organization around ZILRETTA.

Team (Pre-Acquisition)

  • Michael Clayman, M.D. - Founder & CEO
  • Frederick Driscoll - Chief Financial Officer
  • Neil Bodick, M.D., Ph.D. - Chief Scientific Officer

Additional Research Findings

  • Founded in 2007, IPO in February 2014
  • ZILRETTA approved by FDA in October 2017
  • First and only extended-release intra-articular corticosteroid
  • Acquired by Pacira BioSciences in November 2021 for $630 million
  • Portfolio company of 5AM Ventures
  • Had over 200 employees at time of acquisition
  • Key investors included 5AM Ventures, Sofinnova Ventures, and Polaris Partners

Sources

Investors

NameLocationTypeStagesPortfolio
5AM VenturesMenlo Park, USAbiotech-focused
seedseries-a+1
8