Fluent BioSciences

Biotechnology company developing accessible single-cell sequencing technology using PIPseq (Particle-templated Instant Partitions), enabling high-throughput single-cell analysis without specialized equipment.

Location
Watertown, Massachusetts, USA
Founded
2019
Investors
1
Categories
single-cell-sequencing, genomics, sequencing-technology, biotech, life-science-tools

Notes

Fluent BioSciences is a biotechnology company making single-cell sequencing more accessible and affordable through its innovative PIPseq technology. Unlike competing approaches that require expensive microfluidics equipment, PIPseq uses pre-templated particles that work in standard laboratory tubes, dramatically lowering the barrier to entry for single-cell research.

The company emerged from Harvard's Weitz lab and was founded to democratize single-cell genomics. Their technology allows researchers to analyze millions of cells without specialized instruments, making it particularly valuable for large-scale studies and laboratories with limited equipment budgets.

Fluent BioSciences offers kits for single-cell RNA sequencing, ATAC-seq, and multiomics applications. The company has partnerships with major research institutions and has been adopted by academic and pharmaceutical researchers worldwide.

Team

  • Ravi Sheth, Ph.D. - Co-founder & CEO
  • David Weitz, Ph.D. - Scientific Co-founder (Harvard Professor)
  • Adam Sciambi, Ph.D. - Chief Technology Officer

Additional Research Findings

  • Founded in 2019, spun out from Harvard's Weitz lab
  • PIPseq technology enables equipment-free single-cell sequencing
  • No microfluidics required - works in standard lab tubes
  • Raised $45 million Series A in 2021 led by Northpond Ventures
  • Key investors include Northpond Ventures, Novo Holdings, and Alexandria Venture Investments
  • Competes with 10x Genomics, Parse Biosciences, and Scale Biosciences
  • Products include single-cell RNA-seq, ATAC-seq, and multiome kits

Sources

Investors

NameLocationTypeStagesPortfolio
Illumina VenturesSan Francisco, California, USAbiotech-focused
seedseries-a+1
32