Neogene Therapeutics

Cell therapy company developing personalized neoantigen-targeting T cell receptor (TCR) therapies for solid tumors. Acquired by AstraZeneca in 2022 for up to $320 million.

Location
Los Angeles, California, USA & Amsterdam, Netherlands
Founded
2019
Investors
1
Categories
biotech, cell-therapy, oncology, tcr-therapy, personalized-medicine

Notes

Neogene Therapeutics was a clinical-stage cell therapy company focused on developing personalized T cell receptor (TCR) therapies targeting neoantigens in solid tumors. The company's approach involved identifying tumor-specific neoantigens in each patient's cancer and engineering their T cells to recognize and attack these targets.

The company was acquired by AstraZeneca in 2022 for up to $320 million, bringing its neoantigen-targeting TCR platform into AstraZeneca's oncology pipeline to advance cell therapy approaches for solid tumors.

Team

  • Carsten Reinhardt, M.D., Ph.D. - Former Chief Executive Officer
  • Company now part of AstraZeneca

Additional Research Findings

  • Founded in 2019
  • Dual headquarters in Los Angeles, California and Amsterdam, Netherlands
  • Former portfolio company of Polaris Partners
  • Acquired by AstraZeneca in 2022 for up to $320 million
  • TCR-based cell therapies targeting neoantigens
  • Focus on solid tumor treatment
  • Personalized cancer immunotherapy approach
  • Now integrated into AstraZeneca's oncology R&D

Sources

Investors

NameLocationTypeStagesPortfolio
Polaris PartnersUSbiotech-focused-33