NewAmsterdam Pharma

Clinical-stage biopharmaceutical company developing oral, non-statin therapies for patients at risk of cardiovascular disease with elevated LDL-cholesterol, particularly focusing on CETP inhibition.

Location
Naarden, Netherlands
Founded
2019
Categories
biotech, cardiovascular, lipid-disorders, pharmaceuticals

Notes

NewAmsterdam Pharma is a clinical-stage biopharmaceutical company focused on developing novel therapies for patients with cardiovascular disease who have elevated LDL-cholesterol. The company's lead product candidate is obicetrapib, an oral CETP (cholesteryl ester transfer protein) inhibitor that has shown significant LDL-cholesterol lowering in clinical trials.

The company went public on NASDAQ (ticker: NAMS) through a SPAC merger with Frazier Lifesciences Acquisition Corporation in 2022.

Team

  • Michael Davidson, M.D. - Chief Executive Officer
  • John Kastelein, M.D., Ph.D. - Co-Founder & Chief Scientific Officer
  • Daniel O'Day - Board Member

Additional Research Findings

  • Listed on NASDAQ (NAMS) since November 2022
  • Headquarters in Naarden, Netherlands with operations in US
  • Lead candidate: obicetrapib - oral CETP inhibitor for LDL-cholesterol reduction
  • Targeting patients with familial hypercholesterolemia and those intolerant to statins
  • Backed by Bain Capital Life Sciences, Forbion, and other major healthcare investors
  • Completed Phase 3 trials showing 50%+ reduction in LDL-cholesterol
  • Non-statin approach provides alternative for statin-intolerant patients

Sources