Pandion Therapeutics (Acquired by Merck)

Biotechnology company that developed targeted immunotherapies for autoimmune diseases using tissue-specific Treg modulators. Acquired by Merck in 2021 for $1.85 billion.

Location
Watertown, Massachusetts, USA
Founded
2016
Investors
1
Categories
biotech, autoimmune, immunotherapy, acquired

Notes

Pandion Therapeutics was a biotechnology company focused on developing targeted immunotherapies for autoimmune diseases. The company's approach used tissue-specific regulatory T cell (Treg) modulators designed to restore immune tolerance in specific organs affected by autoimmune conditions.

In February 2021, Merck acquired Pandion Therapeutics for approximately $1.85 billion, gaining access to its pipeline of tissue-targeted immunotherapies for autoimmune diseases.

Team (at time of acquisition)

  • Rahul Kakkar, M.D. - Founder & Chief Executive Officer
  • Todd Zion, Ph.D. - Co-Founder & Chief Scientific Officer

Additional Research Findings

  • Founded in 2016 in Watertown, Massachusetts
  • Portfolio company of Polaris Partners
  • Acquired by Merck in February 2021 for ~$1.85 billion
  • Pioneered tissue-targeted Treg modulator approach
  • Lead candidate PT-101 for ulcerative colitis (now in Merck pipeline)
  • Developed TALON (Tissue-specific, Active, Local Delivery of Immunotherapy) platform
  • Programs now advancing under Merck's development

Sources

Investors

NameLocationTypeStagesPortfolio
Polaris PartnersUSbiotech-focused-33