ARCH Venture Partners

One of the most prolific and successful life sciences venture capital firms, known for company creation and backing transformative scientific innovations. Legendary track record including Illumina, Grail, Unity Biotechnology, and numerous breakthrough companies.

Location
Chicago, USA
Founded
1986
AUM
$7B+
Investment Range
$5M - $100M
Portfolio Companies
6
Focus
biotech-focused
Fund Stages
seed, series-a, series-b, series-c, growth

Investment Thesis

ARCH Venture Partners invests at the intersection of technology and life sciences, with a focus on company creation around breakthrough scientific discoveries. They take a hands-on company-building approach, often co-founding companies with scientists and providing extensive operational support from inception through IPO.

Team

Partners / Managing Directors (Health & Bio Focus)

  • Robert Nelsen - Co-Founder & Managing Director
  • Keith Crandell - Co-Founder & Managing Director
  • Kristina Burow - Managing Director
  • Clinton Bybee - Managing Director

Other Key Team Members

  • Steve Gillis, PhD - Managing Director
  • Bob Tabb - Managing Director

Focus Areas

  • Biotechnology
  • Genomics
  • Life Sciences
  • Physical Sciences
  • Drug Discovery
  • Platform Technologies
  • Company Creation

Notable Exits

  • Illumina - IPO (2000, NASDAQ: ILMN) - founded by ARCH
  • Grail - Acquired (2021, by Illumina for $8B)
  • Juno Therapeutics - Acquired (2018, by Celgene for $9B)
  • Kite Pharma - Acquired (2017, by Gilead for $11.9B)
  • Unity Biotechnology - IPO (2018, NASDAQ: UBX)
  • Alnylam Pharmaceuticals - IPO (2004, NASDAQ: ALNY)

Sources

Portfolio Companies

NameLocationFoundedCategories
Mirador TherapeuticsSan Diego, California, USA2023
therapeuticsbiotech+3
IlluminaSan Diego, California, USA1998
genomics-sequencingbiotech+3
Alnylam PharmaceuticalsCambridge, Massachusetts, USA2002
biotechrna-therapeutics+3
bluebird bioSomerville, Massachusetts, USA2010
biotechgene-therapy+4
MetseraNew York, New York, USA2022
therapeuticsbiotech+5
Prime MedicineCambridge, Massachusetts, USA2019
biotechgene-editing+2