Aulos Biosciences

Clinical-stage biotechnology company developing a new class of immunotherapies that selectively activate immune cells to fight cancer while avoiding suppressive regulatory pathways.

Location
Waltham, Massachusetts, USA
Founded
2019
Investors
1
Categories
biotech, immunotherapy, oncology, il-2, therapeutics

Notes

Aulos Biosciences is a clinical-stage biotechnology company developing next-generation immunotherapies for cancer treatment. The company's lead program, AU-007 (Imnekibart), is an anti-IL-2 antibody designed to redirect the body's endogenous IL-2 to activate and expand cancer-fighting immune cells while avoiding regulatory T cells that can suppress anti-tumor immunity.

The company is advancing AU-007 in clinical trials for multiple cancer indications including melanoma and non-small cell lung cancer (NSCLC).

Team

  • Robert Kastelein, M.D., Ph.D. - Co-Founder and CEO
  • Peter van de Vliet, M.D. - Chief Medical Officer
  • David Chang, M.D., Ph.D. - Board Member

Additional Research Findings

  • Lead program AU-007 (Imnekibart) is an anti-IL-2 antibody
  • Focus on redirecting endogenous IL-2 to cancer-fighting immune cells
  • Clinical trials in melanoma and NSCLC
  • Novel approach to overcome limitations of traditional IL-2 therapy
  • Backed by leading biotech investors

Sources

Investors

NameLocationTypeStagesPortfolio
Apple Tree PartnersNew York, USAbiotech-focused
series-aseries-b+2
23